Anti-RBM8A antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q9Y5S9

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre-and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.

RBM8A

Rabbit polyclonal against RBM8A

Nucleus
Nucleus Speckle
Cytoplasm
Nucleocytoplasmic Shuttling Protein
Travels To The Cytoplasm As Part Of The Exon Junction Complex (Ejc) Bound To Mrna
Colocalizes With The Core Ejc
Alyref/Thoc4
Nxf1 And Uap56 In The Nucleus And Nuclear Speckles

WB 1:500-1:2000

Rna-Binding Protein 8a
Binder Of Ovca1-1
Bov-1
Rna-Binding Motif Protein 8a
Rna-Binding Protein Y14
Ribonucleoprotein Rbm8a

RBM8A_HUMAN