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Anti-HAVCR2 antibody

203,00 €
Zzgl. MwSt.
ArtNr STJ115406-50
Hersteller St John's Laboratory
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Hepatitis A Virus Cellular Receptor 2 antibody</br>Anti-Havcr-2 antibody</br>Anti-T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3 antibody</br>Anti-Timd-3 antibody</br>Anti-T-Cell Immunoglobulin Mucin Receptor 3 antibody</br>Anti-Tim-3 an
Similar products Anti-Hepatitis A Virus Cellular Receptor 2 antibody
Anti-Havcr-2 antibody
Anti-T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3 antibody
Anti-Timd-3 antibody
Anti-T-Cell Immunoglobulin Mucin Receptor 3 antibody
Anti-Tim-3 an
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
Q8TDQ0
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto-and alloimmune responses, and promotes immunological tolerance.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-202 of human HAVCR2 (NP_116171. 3).
Short Description
Rabbit polyclonal against HAVCR2
Tissue specificity
Expressed in T-helper type 1 (Th1) lymphocytes. Expressed on regulatory T (Treg) cells after TCR stimulation. Expressed in dendritic cells and natural killer (NK) cells. Expressed in epithelial tissues. Expression is increased on CD4+ and CD8+ T-cells in chronic hepatitis C virus (HCV) infection. In progressive HIV-1 infection, expression is up-regulated on HIV-1-specific CD8 T-cells.
Cellular localization
Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Cell Membrane
Localizes To The Immunological Synapse Between Cd8+ T-Cells And Target Cells
Molecular weight
Calculated: 16kDa/33kDa. Observed: 33kDa
Dilution range
WB 1:500-1:2000 IHC 1:50-1:200
Alternative names
Anti-Hepatitis A Virus Cellular Receptor 2 antibody
Anti-Havcr-2 antibody
Anti-T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3 antibody
Anti-Timd-3 antibody
Anti-T-Cell Immunoglobulin Mucin Receptor 3 antibody
Anti-Tim-3 antibody
Anti-T-Cell Membrane Protein 3 antibody
Anti-Cd Antigen Cd366 antibody
Anti-HAVCR2 TIM3 TIMD3 antibody
Protein name
Hepatitis A Virus Cellular Receptor 2
Havcr-2
T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3
Timd-3
T-Cell Immunoglobulin Mucin Receptor 3
Tim-3
T-Cell Membrane Protein 3
Cd Antigen Cd366
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
Listenpreis: 203,00 €
Preis: 203,00 €
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Lieferung vsl. bis 11.09.2025 

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