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Anti-TPM1 antibody

203,00 €
Zzgl. MwSt.
ArtNr STJ25940-50
Hersteller St John's Laboratory
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Fish
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Tropomyosin Alpha-1 Chain antibody</br>Anti-Alpha-Tropomyosin antibody</br>Anti-Tropomyosin-1 antibody</br>Anti-TPM1 C15orf13 TMSA antibody
Similar products Anti-Tropomyosin Alpha-1 Chain antibody
Anti-Alpha-Tropomyosin antibody
Anti-Tropomyosin-1 antibody
Anti-TPM1 C15orf13 TMSA antibody
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P09493
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPM1 (NP_001018008. 1).
Short Description
Rabbit polyclonal against TPM1
Tissue specificity
Detected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients. Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle.
Cellular localization
Cytoplasm
Cytoskeleton
Associates With F-Actin Stress Fibers
Molecular weight
Calculated: 26kDa/28kDa/32kDa. Observed: 36kDa
Dilution range
WB 1:500-1:2000 IF 1:50-1:200
Alternative names
Anti-Tropomyosin Alpha-1 Chain antibody
Anti-Alpha-Tropomyosin antibody
Anti-Tropomyosin-1 antibody
Anti-TPM1 C15orf13 TMSA antibody
Protein name
Tropomyosin Alpha-1 Chain
Alpha-Tropomyosin
Tropomyosin-1
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
Listenpreis: 203,00 €
Preis: 203,00 €
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Lieferung vsl. bis 28.08.2025 

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