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Anti-AIF-M1 antibody

253,00 €
Zzgl. MwSt.
ArtNr STJ97819-100
Hersteller St John's Laboratory
Menge 100ul
Kategorie
Typ Antibody Monoclonal
Applikationen WB, FC, IF, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Mouse
Isotype IgG2b
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Anti-Apoptosis-Inducing Factor 1-Mitochondrial antibody</br>Anti-Programmed Cell Death Protein 8 antibody</br>Anti-AIFM1 AIF PDCD8 antibody
Similar products Anti-Apoptosis-Inducing Factor 1-Mitochondrial antibody
Anti-Programmed Cell Death Protein 8 antibody
Anti-AIFM1 AIF PDCD8 antibody
Lieferbar
Clonality
Monoclonal
Conjugation
Unconjugated
Formulation
Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
Purification
Affinity purification
Uniprot ID
O95831
Storage
Store at-20° C, and avoid repeat freeze-thaw cycles.
Description
Mouse monoclonal to AIF-M1.
Gene ID
Gene symbol
Immunogen
Purified recombinant fragment of human AIF-M1 expressed in E. Coli.
Short Description
Mouse monoclonal against AIF-M1
Tissue specificity
Expressed in all tested tissues. Detected in muscle and skin fibroblasts (at protein level).; [Isoform 3]: Brain specific.; [Isoform 4]: Expressed in all tested tissues except brain.; [Isoform 5]: Isoform 5 is frequently down-regulated in human cancers.
Cellular localization
Mitochondrion Intermembrane Space
Mitochondrion Inner Membrane
Cytoplasm
Nucleus
Perinuclear Region
Proteolytic Cleavage During Or Just After Translocation Into The Mitochondrial Intermembrane Space (Ims) Results In The Formation Of An Inner-Membrane-Anchored Mature Form (Aifmit)
During Apoptosis
Further Proteolytic Processing Leads To A Mature Form
Which Is Confined To The Mitochondrial Ims In A Soluble Form (Aifsol)
Aifsol Is Released To The Cytoplasm In Response To Specific Death Signals
And Translocated To The Nucleus
Where It Induces Nuclear Apoptosis
Colocalizes With Eif3g In The Nucleus And Perinuclear Region
Isoform 3: Mitochondrion Intermembrane Space
Has A Stronger Membrane Anchorage Than Isoform 1
Isoform 4: Mitochondrion
Cytosol
In Pro-Apoptotic Conditions
Is Released From Mitochondria To Cytosol In A Calpain/Cathepsin-Dependent Manner
Isoform 5: Cytoplasm
Dilution range
WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000
Alternative names
Anti-Apoptosis-Inducing Factor 1-Mitochondrial antibody
Anti-Programmed Cell Death Protein 8 antibody
Anti-AIFM1 AIF PDCD8 antibody
Protein name
Apoptosis-Inducing Factor 1-Mitochondrial
Programmed Cell Death Protein 8
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
Listenpreis: 253,00 €
Preis: 253,00 €
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Lieferung vsl. bis 11.09.2025 

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