CD28H Recombinant Protein

749,00 €

Zzgl. MwSt.

ArtNr	PRS-96-844-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Western Blot Butyrophilins
Typ	Proteins Recombinant
Format	Lyophilized
Applikationen	WB
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TMIGD2,IGPR1
Lieferbar
Applications	This recombinant protein can be used for WB. For research use only.
Applications	This recombinant protein can be used for WB. For research use only.
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	40.6 kDa
Purity	>95% as determined by SDS-PAGE. Endotoxin level is less than 1.0 EU per ug by the LAL method.
Background	CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1, is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue, the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
1St Image Caption3	Human CD28H / IGPR-1, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Background References 1	Zhu, Y. et al., 2013, Nat. Commun., 4:2043.
Background References 2	Rahimi, N. et al., 2012, Mol. Biol. Cell., 23(9):1646-1656.
Background References 3	Kaneko, T. et al., 2008, Front. Biosci., 13:4938.
Accession #	AAH15655.1
Ncbi Gene Id #	126259
Ncbi Official Symbol	CD28H
Ncbi Official Full Name	Transmembrane and immunoglobulin domain containing 2
Ncbi Organism	Homo sapiens
Swissprot #	Q96BF3-1
Fusion Tag	Fc Tag
Sequence	Leu 23 - Gly 150
Peptide Sequence	Leu 23 - Gly 150

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

Listenpreis: 749,00 €

Preis: 749,00 €

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