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LAG-3 Recombinant Protein

678,00 €
Zzgl. MwSt.
ArtNr PRS-90-246-50ug
Hersteller ProSci
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against other
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Lymphocyte Activation Gene-3, FDC Protein, CD223
Lieferbar
Applications
This recombinant proteins is for research use only.
Applications
This recombinant proteins is for research use only.
Buffer
In PBS.
Storage Conditions
Stable for at least 6 months after receipt when stored at +4˚ C.
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Purity
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μ g purified protein (LAL test; Lonza).
Background
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Concentration
0.5 mg/ml
Accession #
Q61790
Ncbi Gene Id #
16768
Ncbi Official Symbol
LAG3
Ncbi Official Full Name
lymphocyte-activation gene 3 
Ncbi Organism
Mus musculus
Swissprot #
P55036
Fusion Tag
Fc Tag
Sequence
The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
Biological Activity
Induces maturation of mouse dendritic cells in vitro. Induces CD4 and CD8 antigen-specific T cells responses when coinjected s.c. in mice, together with the antigen.
Protein Gi#
2497295

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
Listenpreis: 678,00 €
Preis: 678,00 €
lieferbar

Lieferung vsl. bis 04.09.2025 

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