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IL-17A Recombinant Protein

IL-17A Recombinant Protein

314,00 €

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ArtNr	PRS-40-423-0.005mg
Hersteller	ProSci
Menge	0.005 mg
Kategorie	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Typ	Proteins Recombinant
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Il17, Ctla8, IL-17, Ctla-8, IL-17A, Il17, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8
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Storage Conditions	The lyophilized IL-17A recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-17A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-17A recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Disclaimer	This product is for research use only.
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per μ g (1EU/μ g).
Background	The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant murine IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains.
Accession #	NP_034682.1
Ncbi Gene Id #	16171
Ncbi Official Symbol	Il17a
Ncbi Official Full Name	interleukin 17A
Ncbi Organism	Mus musculus
Swissprot #	Q62386
Sequence	MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA
Biological Activity	Biological activity was measured by its ability to induce IL - 6 production by NIH 3T3 cells.
Protein Gi#	6754324
Peptide Sequence	MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.005 mg

Listenpreis: 314,00 €

Preis: 314,00 €

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