Recombinant human KIR2DS4/CD158i protein

Human

An activating Killer Cell Ig-like Receptor (KIR, previously called p50 KIR, p50. 3, cl39, or KAR-K1), which may recognize class I MHC molecules. The protein coding region of the extracellular domain of KIR2DS4 (amino acids 1-202) was cloned into an E. coli expression vector. The extracellular domain of KIR2DS4 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant KIR2DS4 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.

Liquid in. 20mM Tris-HCl buffer (pH 7.5)

Steffens u., et al. (1998) Tissue Antigens 51, 398-413.; ; Wagtmann N., et al. (1995) Immunity. 2, 439-449.; ;

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.