Recombinant human CD40 Ligand/TNFSF5 protein

Measured by its binding ability in a functional ELISA with Human CD40/TNFRSF5 (CAT# ATGP4007)

MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LCLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL

CD40 ligand, also known as CD40LG, is a member of the TNF superfamily and is expressed on activated T cells. CD40LG is expressed as a soluble cytokine as well as a homotrimeric type II transmembrane protein. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Mutations in the gene encoding for CD154 are implicated in hyper-IgM immunodeficiency syndrome type 1. Recombinant human CD40LG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

< 1 EU per 1ug of protein (determined by LAL method)

Immunology

CD40 Ligand, TNFSF5, CD40 ligand, CD154, CD40L, gp39, hCD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, ATGP4019-10ug, ATGP4019-20ug, ATGP4019-50ug, ATGP4019-100ug, ATGP4019-250ug, ATGP4019-500ug, ATGP4019-1mg, ATGP4019-10, ATGP4019-20, ATGP4019-50, ATGP4019-100, ATGP4019-250, ATGP4019-500, ATGP4019-1

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.