Recombinant human CD30/TNFRSF8 protein

FPQDRPF EDTCHGNPSH YYDKAVRRCC YRCPMGLFPT QQCPQRPTDC RKQCEPDYYL DEADRCTACV TCSRDDLVEK TPCAWNSSRV CECRPGMFCS TSAVNSCARC FFHSVCPAGM IVKFPGTAQK NTVCEPASPG VSPACASPEN CKEPSSGTIP QAKPTPVSPA TSSASTMPVR GGTRLAQEAA SKLTRAPDSP SSVGRPSSDP GLSPTQPCPE GSGDCRKQCE PDYYLDEAGR CTACVSCSRD DLVEKTPCAW NSSRTCECRP GMICATSATN SCARCVPYPI CAAETVTKPQ DMAEKDTTFE APPLGTQPDC NPTPENGEAP ASTSPTQSLL VDSQASKTLP IPTSAPVALS STGK

TNFRSF8, also known as Tumor necrosis factor receptor superfamily member 8, is receptor for TNFSF8/CD30L. It may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Also, this protein regulates gene expression through activation of NF-kappa-B. As a regulator of apoptosis, TNFRSF8 induces cell death or proliferation, depending on the cell type. Recombinant human TNFRSF8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

< 1 EU per 1ug of protein (determined by LAL method)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Yao J., et al. (2013) Am. J. Surg. Pathol. 37(9):1407-1412.; ; Velasquez SY., et al. (2013) Transplantation 96(2):154-161.