Human Galectin-9 / LGALS9 Protein, His Tag

20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4

Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for beta-galactoside sugars, such as N-acetyllactosamine (Galbeta1-3GlcNAc or Galbeta1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

Ala 2 - Thr 323

36.6 kDa

RT