BDNF, Mouse (R129A, R130A, HEK293, C-His)

BDNF protein, a crucial signaling molecule, activates NTRK2 downstream cascades, influencing diverse roles in neuronal development and function. It promotes survival and differentiation in both peripheral and central nervous systems, impacting axonal and dendritic growth. BDNF is a major regulator of synaptic transmission and plasticity, contributing to adaptive responses like LTP, LTD, and neuronal excitability regulation. Its interaction with NGFR and SORCS2 is implicated in neuronal apoptosis and growth cone collapse, emphasizing its multifaceted impact on neuronal physiology and development. BDNF Protein, Mouse (R129A, R130A, HEK293, C-His) is the recombinant mouse-derived BDNF protein, expressed by HEK293 , with C-6*His labeled tag and R129A, R130A mutation. The total length of BDNF Protein, Mouse (R129A, R130A, HEK293, C-His) is 231 a.a., with molecular weight of ~35-42 kDa.

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Recombinant Proteins