TIM-3/HAVCR2 Protein, Human (HEK293, His)

T cell immunoglobulin mucin-3 is an inhibitory receptor, and inhibits T cell functions. TIM-3 regulates immune responses in autoimmunity and cancer. TIM-3 has multiple different ligands: galectin 9, phosphatidylserine (PtdSer), CEACAM1 and HMGB1. The TIM-3-ligand axis is critical in the pathogenesis of numerous conditions, including autoimmune diseases, infections, cancers, transplant rejection, and chronic inflammation[1][2][3][4][5]. TIM-3/HAVCR2 Protein, Human (HEK293, His) is the recombinant human-derived TIM-3/HAVCR2 protein, expressed by HEK293, with C-6*His labeled tag. The total length of TIM-3/HAVCR2 Protein, Human (HEK293, His) is 179 a.a., with molecular weight of ~37.0 kDa.

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Recombinant Proteins