Erythropoietin receptor/EpoR Protein, Human (226a.a, HEK293, His)

The EPOR Protein functions as a receptor for erythropoietin, mediating erythroblast proliferation and differentiation upon EPO stimulation. The heterodimer triggers the JAK2/STAT5 signaling cascade and, in certain cell types, activates STAT1, STAT3, and the LYN tyrosine kinase. Additionally, isoform EPOR-T acts as a dominant-negative receptor, modulating EPOR-mediated signaling pathways. Erythropoietin receptor/EpoR Protein, Human (226a.a, HEK293, His) is the recombinant human-derived Erythropoietin receptor/EpoR protein, expressed by HEK293, with C-6*His labeled tag. The total length of Erythropoietin receptor/EpoR Protein, Human (226a.a, HEK293, His) is 226 a.a., with molecular weight of approximately 32.54 kDa.

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Recombinant Proteins