Human TIM3 Protein, mFc-His Tag

Blue Ice

Store at -80C for 12 months (Avoid repeated freezing and thawing)

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 37 % trehalose is added as protectants before lyophilization.

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Q8TDQ0

TIM3

HEK293

> 95%

TIM3(Ser22-Gly202)+mFc(Pro99-Lys330)+6xHis tag