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Human CD3 epsilon&CD3 delta Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Human CD3 epsilon&CD3 delta Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

402,00 €

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ArtNr	CDD-H5255-100ug
Hersteller	ACROBiosystems
Menge	100ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Fc
Purity	>90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD3E & CD3D,CD3 delta & CD3 epsilon,CD3 delta , epsilon
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Bioactivity Legend 1	Immobilized Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDD-H5255) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), Ultra-low endotoxin (Cat. No. CDE-M120a) with a linear range of 0.8-6 ng/mL (QC tested).
Bioactivity Legend 2	Immobilized Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDD-H5255) at 1 ug/mL (100 uL/well) can bind Mouse Anti Human CD3 with a linear range of 0.8-6 ng/mL (Routinely tested).
Buffer	PBS, pH7.4
Characteristics	Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3D, has a calculated MW of 38.3 kDa (CD3E) and 35.8 kDa (CD3D). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3D is fused with a human IgG1 Fc tag at the C-terminus. As a result of glycosylation, the protein migrates as 45-60 kDa under reducing (R) condition, and 90-110 kDa under non-reducing (NR) condition (SDS-PAGE).
Description	T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D)
Expression System	HEK293
Molecular Weight	38.3 kDa (CD3E) & 35.8 kDa (CD3D)
Molecule	CD3E & CD3D
SDS-PAGE Legend	Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Storage	-20C
Host Information	Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag (CDD-H5255) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P07766-1 (CD3E) & P04234-1 (CD3D)).

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Menge: 100ug

Listenpreis: 402,00 €

Preis: 402,00 €

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Lieferung vsl. bis 11.09.2025

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