Recombinant human CD277/BTN3A1 protein

SDS-PAGE

BTN3A1, also known as butyrophilin subfamily 3 member A1 isoform, belongs to the immunoglobulin superfamily. It is composed of an extracellular N-terminal IgV and a membrane proximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. This protein plays a role in T-cell activation and in the adaptive immune response. Also, it regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Recombinant human BTN3A1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

< 1.0 EU per 1ug of protein (determined by LAL method)

Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

Rhodes DA., et al, (2015) J. Immunol. 194:2390-2398.
Sandstrom A., et al, (2014) Immunity 40:490-500.

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.