Octreotide

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ArtNr	HY-P0036-1mg
Hersteller	MedChem Express
CAS-Nr.	83150-76-9
Menge	1 mg
Kategorie	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Peptides
Typ	Peptides
Specific against	other
Purity	99.64
Formula	C49H66N10O10S2
Citations	Basic Clin Pharmacol Toxicol. 2022 Jun 10. Cell Mol Bioeng. 2022. Faculty of Biological and Environmental Sciences. University of Helsinki Finland. 2018 Dec. J Pharm Biomed Anal. 11 December 2021, 114518. J Pharm Biomed Anal. 2022: 115156. J Pharm Sci. 2022 Oct 10;S0022-3549(22)00454-3. Nat Commun. 2023 Feb 21;14(1):962. Research Square Print. 2022 Aug. [1]Wang XX, et al. Effects of octreotide on hepatic glycogenesis in rats with high fat diet?induced obesity. Mol Med Rep. 2017 Jul;16(1):109-118 [2]Kugita M, et al. Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease. PLoS One. 2017 May 18;12(5):e0177934. [3]Xiao-Xia Wang,et al. Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity. Mol Med Rep. 2017 Jul;16(1):109-118.
Smiles	O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)C(N[C@H](CO)[C@H](O)C)=O)NC([C@H](N)CC2=CC=CC=C2)=O)=O)CC3=CC=CC=C3)N[C@@H]1CC4=CNC5=CC=CC=C45
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SMS 201-995
Lieferbar
Product Description	Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly[1][2].
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	1019.24
Clinical Information	Launched
Solubility	H2O : 100 mg/mL (ultrasonic)
Isoform	SSTR2; SSTR3; SSTR5
Pathway	Apoptosis; GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Peptides

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HY-P0036-1mg-safety-datasheet.pdf