6-Hydroxyflavone

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ArtNr	HY-N7110-100mg
Hersteller	MedChem Express
CAS-Nr.	6665-83-4
Menge	100 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.95
Formula	C15H10O3
Citations	[1]Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52. [2]Lai CH, et al. Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells. Evid Based Complement Alternat Med. 2014;2014:924560. [3]Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409.
Smiles	O=C1C=C(C2=CC=CC=C2)OC3=CC=C(O)C=C13
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	6665-83-4
Lieferbar
Product Description	6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	238.24
Clinical Information	No Development Reported
Solubility	DMSO : 125 mg/mL (ultrasonic)
Pathway	MAPK/ERK Pathway; PI3K/Akt/mTOR; Stem Cell/Wnt
Manufacturers Product type	Natural Products

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HY-N7110-100mg-safety-datasheet.pdf