Ciprofloxacin

106,00 €

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ArtNr	HY-B0356-5g
Hersteller	MedChem Express
CAS-Nr.	85721-33-1
Menge	5 g
Kategorie	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Purity	99.86
Formula	C17H18FN3O3
Citations	Adv Sci (Weinh). 2020 Jul 21;7(17):2001374. Anal Chim Acta. 15 June 2022, 340082. Animal Diseases. 02 November 2021. Appl Microbiol Biotechnol. 2022 Apr;106(7):2689-2702. Chemosphere. 2019 Jun;225:378-387. EBioMedicine. 2022 Apr;78:103943. Front Microbiol. 2022 Feb 16;12:773664. Genome Biol. 2023 Apr 30;24(1):98. Int J Antimicrob Agents. 2018 Aug;52(2):269-271. iScience. 2023 Oct 5. J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858. Microbiol Spectr. 2022 Apr 25:e0251821. Microbiol Spectr. 2022 Jan 12;e0099121. Molecules. 2023 Jun 8, 28(12), 4628. Patent. US20200101105A1. Research Square Preprint. 2020 Jun. Water Res. 2023 May 21, 120110. ACS Appl Polym Mater. 2023 Aug 29. Animal Diseases. 02 November 2021. Nat Commun. 2022 Mar 2;13(1):1116. [1]LeMaire SA, et, al. Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice. JAMA Surg. 2018 Sep 1;153(9):e181804. [2]Tsai WC, et, al. Ciprofloxacin-mediated cell proliferation inhibition and G2/M cell cycle arrest in rat tendon cells. Arthritis Rheum. 2008 Jun;58(6):1657-63. [3]Steenbergen J, et, al. In Vitro and In Vivo Activity of Omadacycline against Two Biothreat Pathogens, Bacillus anthracis and Yersinia pestis. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02434-16. [4]Hamblin KA, et, al. Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague. Front Microbiol. 2017 Feb 6;8:91.
Smiles	O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCNCC4)=C3)C1=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Bay-09867
Lieferbar
Product Description	Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	331.34
Clinical Information	Launched
Solubility	0.1 M HCL : 16.67 mg/mL (ultrasonic; warming; adjust pH to 2 with HCl; heat to 60°C)
Isoform	Quinolone
Pathway	Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Reference compound

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