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Omadacycline tosylate

Omadacycline tosylate

1.133,00 €

Zzgl. MwSt.

ArtNr	HY-14865B-50mg
Hersteller	MedChem Express
CAS-Nr.	1075240-43-5
Menge	50 mg
Kategorie	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Sarcoma Cell Biology Cell Status Cytoskeleton Proliferation Inhibitors & Compound Libraries Small Molecules Intermediate filaments By Organ Bladder Cancer Breast Cancer
Typ	Inhibitors
Purity	99.37
Formula	C36H48N4O10S
Citations	[1]Tanaka SK, et al. In Vitro and In Vivo Assessments of Cardiovascular Effects with Omadacycline. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5247-53. [2]Durães F, et, al. Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines. Pharmaceuticals (Basel). 2019 Apr 21;12(2):63. [3]Macone AB, et, al. In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcycline. Antimicrob Agents Chemother. 2014;58(2):1127-35. [4]Zhanel GG, et, al. Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent. Drugs. 2020 Feb;80(3):285-313. [5]Markham A, et, al. Omadacycline: First Global Approval. Drugs. 2018 Dec;78(18):1931-1937.
Smiles	O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.OS(=O)(C5=CC=C(C)C=C5)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PTK 0796 (tosylate); Amadacycline (tosylate)
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Product Description	Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	728.85
Clinical Information	Launched
Solubility	H2O : 12.5 mg/mL (ultrasonic)
Isoform	Tetracycline
Pathway	Anti-infection
Manufacturers Product type	Reference compound

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Menge: 50 mg

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Preis: 1.133,00 €

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