ACE2 Protein, Rat (HEK293, His)

ACE2, a crucial carboxypeptidase in the renin-angiotensin system, intricately regulates cardiovascular homeostasis. Its specificity converts angiotensin I to angiotensin 1-9 and angiotensin II to angiotensin 1-7, exerting anti-hypertrophic effects and vasodilation. Beyond angiotensin, ACE2 cleaves vasoactive peptides like neurotensin. Noteworthy, ACE2 is pivotal in amino acid transport, binding to SLC6A19 in the intestine, modulating trafficking, surface expression, and catalytic activity, contributing significantly to amino acid transport regulation. ACE2 Protein, Rat (HEK293, His) is the recombinant rat-derived ACE2 protein, expressed by HEK293, with C-His labeled tag. The total length of ACE2 Protein, Rat (HEK293, His) is 723 a.a., with molecular weight of 105-120 kDa.

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Recombinant Proteins