BDNF, human recombinant

BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability (UniProt)

1 mg/ml

Mature BDNF, Approximately 13.5 kDa, a single non-glycosylated polypeptide chain containing 118 amino acids

Store at -70C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles