Vergleich

Synaptophysin (ready-to-use)

ArtNr 18-272-198129
Hersteller GENWAY
Menge 7 ml
Kategorie
Typ Antibody
Applikationen IHC
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-E14FF5
Similar products 18-272-198129
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Genway ID:
GWB-E14FF5
Immunogen:
Synthetic human synaptophysin peptide.
Antigen Species:
Human
Specificity:
Reacts with a hydrophilic peptide sequence of synaptophysin. Synaptophysin is a useful marker for the identification of normal neuroendocrine cells and neuroendocrine neoplasms.
Positive Control:
Pancreas
Target:
Synaptophysin
Concentration:
ready-to-use Storage
Buffer:
Primary Antibody Diluting Buffer pH 7. 6
Application Note:
This antibody is prediluted for Immunohistochemistry use. The prediluted antibody can be used on frozen cryostat sections as well as formalin-fixed paraffin-embedded tissue sections. For paraffin-embedded tissue sections we recommend an incubation time and temperature of 30 minutes at 37C for this antibody when used in conjunction with \' s immunoperoxidase staining kit. *Prolonged fixation in buffered formalin can destroy the epitope. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Function:
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.
Subunit:
Homohexamer or homotetramer.
Subcellular Location:
Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane; Multi-pass membrane protein. Cell junction synapse synaptosome.
Tissue Specificity:
Characteristic of a type of small (30-80 nm) neurosecretory vesicles including presynaptic vesicles but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Domain:
The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
Ptm:
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation (By similarity).
Similarity:
Belongs to the synaptophysin/synaptobrevin family.
Similarity:
Contains 1 MARVEL domain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 7 ml
Lieferbar: In stock
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Lieferung vsl. bis 11.09.2025 

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