ESRRG Polyclonal Antibody

DKFZp781L1617, ERR 3, ERR G2, ERR gamma 2, ERR gamma-2, ERR3, ERR3, ERRG 2, ERRG2, ERRgamma, ESRRG, Estrogen receptor related protein 3, Estrogen receptor-related protein 3, Estrogen-related receptor gamma, FLJ16023, KIAA0832, NR3B3, Nuclear receptor subfamily 3 group B member 3

This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

WB 1:500-1:2000, IHC 1:50-1:200

51kDa

sc-50932, sc-66883, sc-133561