« Zurück
Startseite /
Recombinant Human Neuroserpin protein(SERPINI1) (Active)

Recombinant Human Neuroserpin protein(SERPINI1) (Active)

156,00 €

Zzgl. MwSt.

ArtNr	CSB-AP000141HU-5
Hersteller	Cusabio
Menge	5ug
Kategorie	Food Safety Proteins Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins Glial Cell Markers
Typ	Proteins
Specific against	other
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Peptidase inhibitor 12, Serpin I1
Lieferbar
Classification	Enzyme
Subdivision	Enzyme
Research Areas	Neuroscience
Uniprot NO.	Q99574
Uniprot Entry Name	NEUS_HUMAN
Gene Names	SERPINI1, PI12
Source	E.Coli
Expression Region	17-406aa
Sequence	TGATFPEEAI ADLSVNMYNR LRATGEDENI LF SPLSIALA MGMMELGAQG STQKEIRHSM GYDS LKNGEE FSFLKEFSNM VTAKESQYVM KIANSL FVQN GFHVNEEFLQ MMKKYFNAAV NHVDFSQN VA VANYINKWVE NNTNNLVKDL VSPRDFDAAT YLALINAVYF KGNWKSQFRP ENTRTFSFTK D DESEVQIPM MYQQGEFYYG EFSDGSNEAG GIY QVLEIPY EGDEISMMLV LSRQEVPLAT LEPLV KAQLV EEWANSVKKQ KVEVYLPRFT VEQEIDL KDV LKALGITEIF IKDANLTGLS DNKEIFLSK A IHKSFLEVNE EGSEAAAVSG MIAISRMAVL YPQVIVDHPF FFLIRNRRTG TILFMGRVMH PE TMNTSGHD
Protein Description	Partial
Tag Info	Tag-Free
Mol. Weight	44.7 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.5 ug/ml, corresponding to a specific activity of > 2000 IU/mg.
Purity	>95% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.5 , lyophilized
Alias	Peptidase inhibitor 12, Serpin I1
Relevance	Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
PubMed ID	9070919; 14702039; 17974005; 15489334; 10517635
Function	Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin
Involvement in disease	Encephalopathy, familial, with neuroserpin inclusion bodies (FENIB)
Subcellular Location	Secreted, Cytoplasmic vesicle, secretory vesicle lumen, Perikaryon
Protein Families	Serpin family
Tissue Specificity	Detected in brain cortex and hippocampus pyramidal neurons (at protein level) (PubMed:17040209). Predominantly expressed in the brain (PubMed:9070919).

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CSB-AP000141HU-5-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 5ug

Listenpreis: 156,00 €

Preis: 156,00 €

lieferbar

Anzahl:

Vergleichen

Auf den Wunschzettel