Histone H4K20me3 Antibody

H4, H4/n, H4F2, H4FN, FO108, HIST2H4

Q16695

ELISA, WB, IF, IP, ChIP, WB:1:500-1:2000, IF:1:50-1:200, IP:1:50-1:200, ChIP:1:50-1:200

WB:1:500-1:2000

IP:1:50-1:200

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Antigen Affinity Purified

Epigenetics and Nuclear Signaling