CTLA4 Antibody

CTLA4, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12

P16410

ELISA, WB, IHC, WB:1:500-1:2000, IHC:1:50-1:200

WB:1:500-1:2000

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Affinity purification

Immunology, Stem cells