FSHB polyclonal antibody

P01225

Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common alpha subunit and a homologous but distinct beta subunit. While the alpha subunit of FSH is involved in the binding of FSH to the receptor (follicle-stimulating hormone receptor, also known as FSHR), the beta subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, posttranslational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

FSHB pAb detects endogenous levels of FSHB protein.

ca. 15 kDa

Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain, FSHB