Recombinant Human CD44 Protein

This protein is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Proteins

Gln21-Pro220

Bio-Markers & CD Antigens, Biosimilar Drug Targets

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.

Measured by its binding ability in a functional ELISA. Immobilized Hyaluronic Acid at 100 μg/mL (100 μL/well) can bind Human CD44 with a linear range of 20-330 ng/mL.