Anti-CXCR2 Antibody

366,00 €

Zzgl. MwSt.

ArtNr	BOS-PA1029
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Murphy P.M., Tiffany H.L.;"Cloning of complementary DNA encoding a functional human interleukin-8 receptor."; Science 253:1280-1283(1991). 2. Cerretti D.P., Kozlosky C.J., Vanden Bos T., Nelson N., Gearing D.P., Beckmann M.P.; "Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2."; Mol. Immunol. 30:359-367(1993). 3. Sprenger H., Lloyd A.R., Lautens L.L., Bonner T.I., Kelvin D.J.;"Structure, genomic organization, and expression of the human interleukin-8 receptor B gene.";J. Biol. Chem. 269:11065-11072(1994).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C-X-C chemokine receptor type 2;CXC-R2;CXCR-2;CDw128b;GRO/MGSA receptor;High affinity interleukin-8 receptor B;IL-8R B;IL-8 receptor type 2;CD182;CXCR2;IL8RB;
Similar products	C-X-C chemokine receptor type 2 antibody, CD 182 antibody, CD182 antibody, CD182 antigen antibody, CDw128b antibody, Chemokine(CXC) receptor 2 antibody, CMKAR2 antibody, CXC-R2 antibody, CXCR 2 antibody, CXCR-2 antibody, CXCR2 antibody, CXCR2_HUMAN antibody, GRO/MGSA receptor antibody, High affinity interleukin-8 receptor B antibody, IL 8 receptor type 2 antibody, IL 8R B antibody, IL-8 receptor type 2 antibody, IL-8R B antibody, IL8 RB antibody, IL8 receptor type 2 antibody, IL8R B antibody, IL8R2 antibody, IL8RA antibody, Interleukin 8 Receptor B antibody
Lieferbar
Specificity	No cross reactivity with other proteins.
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Cell Biology, Cell Cycle, Cell Division, G Protein Signaling, Signal Transduction, Signaling Pathway
Short Description	Boster Bio Anti-CXCR2 Antibody catalog # PA1029. Tested in WB applications. This antibody reacts with Human, Rat.
Description	Boster Bio Anti-CXCR2 Antibody catalog # PA1029. Tested in WB applications. This antibody reacts with Human, Rat.
Background	CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Gene Name	CXCR2
Application Details	Western blot, 0.1-0.5μg/ml, Human, Rat
Application Notes	Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	C-X-C chemokine receptor type 2
Molecular Weight	40759 MW
Protein Function	Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular Localization	Cell membrane; Multi-pass membrane protein.
Protein Name	C-X-C chemokine receptor type 2(CXC-R2/CXCR-2)
Sequence Similarities	Belongs to the G-protein coupled receptor 1 family.

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