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Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Monoclonal Antibody

652,00 €
Zzgl. MwSt.
ArtNr BOS-M01225
Hersteller Boster
Menge 100ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC, IF, IHC
Clon SPM609
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Tumor necrosis factor receptor superfamily member 8;CD30L receptor;Ki-1 antigen;Lymphocyte activation antigen CD30;CD30;TNFRSF8;CD30, D1S166E;
Lieferbar
Manufacturers Product Category
Primary Antibodies, Monoclonal Antibodies
Manufacturers Research Category
Cancer, Cell Type Markers, Cytokines, Immunology, Innate Immunity, Receptors, TNF Superfamily, Tumor Biomarkers, Tumor Immunology
Short Description
Boster Bio Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Monoclonal Antibody (Catalog # M01225). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Description
Boster Bio Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Monoclonal Antibody (Catalog # M01225). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Background
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin' s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Gene Name
TNFRSF8
Clonality
Monoclonal
Concentration
Purified antibody with BSA and azide at 200ug/ml
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Application Details
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Immunogen
Recombinant human TNFRSF8 protein
Purification
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Gene Full Name
Tumor necrosis factor receptor superfamily member 8
Molecular Weight
63747 MW
Protein Function
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Subcellular Localization
Cell surface

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ug
Lieferbar: In stock
Listenpreis: 652,00 €
Preis: 652,00 €
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Lieferung vsl. bis 18.09.2025 

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