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Anti-TrkC/NTRK3 Antibody

366,00 €
Zzgl. MwSt.
ArtNr BOS-PA1992
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NT-3 growth factor receptor;2.7.10.1;GP145-TrkC;Trk-C;Neurotrophic tyrosine kinase receptor type 3;TrkC tyrosine kinase;NTRK3;TRKC;
Similar products EC 2.7.10.1 antibody, ETS related protein neurotrophic receptor tyrosine kinase fusion antibody, ETV6 NTRK3 fusion antibody, GP145 TrkC antibody, gp145(trkC) antibody, GP145-TrkC antibody, GP145TrkC antibody, Neurotrophic tyrosine kinase receptor type 3 antibody, Neurotrophin 3 receptor antibody, NT 3 growth factor receptor antibody, NT 3 growth factor receptor precursor antibody, NT 3 receptor antibody, NT-3 growth factor receptor antibody, Ntrk3 antibody, NTRK3_HUMAN antibody, OTTHUMP00000192915 antibody, TRK C antibody, Trk-C antibody, TrkC tyrosine kinase antibody, Tyrosine kinase receptor C antibody
Lieferbar
Manufacturers Product Category
Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category
Cancer, Growth and Development, Metabolism, Metabolism Processes, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes
Short Description
Boster Bio Anti-TrkC/NTRK3 Antibody catalog # PA1992. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-TrkC/NTRK3 Antibody catalog # PA1992. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Background
NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al. (1994) mapped the NTRK3 gene to 15q24-q25. Lamballe et al. (1991) isolated and characterized TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain; in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, Muinos-Gimeno et al. (2009) demonstrated that 5 miRNAs regulate the truncated form of NTRK3.
Gene Name
NTRK3
Application Details
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Application Notes
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Predicted Reactivity
Bovine
Clonality
Polyclonal
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human TrkC, different from the related rat and mouse sequences by three amino acids.
Purification
Immunogen affinity purified.
Cross-reactivity
No cross-reactivity with other proteins
Storage
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name
NT-3 growth factor receptor
Molecular Weight
94428 MW
Protein Function
Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Tissue Specificity
Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.
Protein Name
NT-3 growth factor receptor
Sequence Similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
Listenpreis: 366,00 €
Preis: 366,00 €
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Lieferung vsl. bis 18.09.2025 

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