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TRPM2 polyclonal antibody

TRPM2 polyclonal antibody

315,00 €

Zzgl. MwSt.

ArtNr	BS7930-50
Hersteller	Bioworld Technology, Inc
Menge	50ul
Kategorie	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Lipid & Fatty Acid Transport Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	EREG 1, EREG1, Estrogen responsive element associated gene 1, Estrogen responsive element associated gene 1 protein, Estrogen-responsive element-associated gene 1 protein, KNP 3, KNP3, Long transient receptor potential channel 2, LTRPC 2, LTrpC-2
Similar products	TRPM2
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Swiss-Prot	O94759
Application all	WB: 1:500ca.1:2000 IHC: 1:50ca.1:200
Background	Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	TRPM2 pAb detects endogenous levels of TRPM2 protein.
BiowMW	ca. 171 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	EREG 1, EREG1, Estrogen responsive element associated gene 1, Estrogen responsive element associated gene 1 protein, Estrogen-responsive element-associated gene 1 protein, KNP 3, KNP3, Long transient receptor potential channel 2, LTRPC 2, LTrpC-2, LTRPC2, MGC133383, NUDT9H, NUDT9L1, putative Ca2+ channel protein, transient receptor potential cation channel subfamily M member 2, Transient receptor potential channel 7, TRPC 7, TRPC7, TRPM 2, Trpm2, TRPM2_HUMAN,
Immunogen	Recombinant full length Human TRPM2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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