FSHB polyclonal antibody

P01225

Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common alpha subunit and a homologous but distinct beta subunit. While the alpha subunit of FSH is involved in the binding of FSH to the receptor (follicle-stimulating hormone receptor, also known as FSHR), the beta subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, posttranslational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

FSHB pAb detects endogenous levels of FSHB protein.

ca. 15 kDa

Follicle Stimulating Hormone, Follicle Stimulating Hormone, Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin beta chain precursor, Follitropin subunit beta, FSH B, FSH-B, FSH-beta, FSHB, FSHbeta, FSHbeta