mAChR M2 polyclonal antibody

P08172

The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

mAChR M2 pAb detects endogenous levels of mAChR M2 protein.

Immunofluorescence analysis of MCF7 cells, using mAChR M2 polyclonal antibody

For research use only, not for use in diagnostic procedure.

Recombinant full length Human mAChR M2.