RanBP9 monoclonal antibody

Q96S59

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins

Immunocytochemistry stain of Hela using RANBP9 antibody (1:300).

Predicted band size:78KDa
Observed band size:95KDa

BPM-L, BPM90, Ran-binding protein M, RanBPM, RanBP7, BPM-L, BPM90, RANBPM, RanBP7