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Anti-Mouse CD3 SAFIRE Size 500 ug

Anti-Mouse CD3 SAFIRE Size 500 ug

222,00 €

Zzgl. MwSt.

ArtNr	05112-25-500
Hersteller	BioGems
Menge	500 ug
Kategorie	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies
Typ	Antibody
Format	SAFIRE Purified
Applikationen	FC, IP, IHC
Clon	17A2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Description	The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ , δ , and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.
Research Interest	Adaptive Immunity
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References	Miescher, G. C., Schreyer, M., & MacDonald, H. R. (1989). Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex. Immunology letters, 23(2), 113-118. Mysliwietz, J., & Thierfelder, S. (1992). Antilymphocytic antibodies and marrow transplantation. XII. Suppression of graft-versus-host disease by T-cell-modulating and depleting antimouse CD3 antibody is most effective when preinjected in the marrow recipient. Blood, 80(10), 2661-2667. Wu, L., Antica, M., Johnson, G. R., Scollay, R., & Shortman, K. (1991). Developmental potential of the earliest precursor cells from the adult mouse thymus. The Journal of experimental medicine, 174(6), 1617-1627.

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Menge: 500 ug

Listenpreis: 222,00 €

Preis: 222,00 €

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Lieferung vsl. bis 27.11.2025

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