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TGFBR1 Antibody (Phospho-S165) (OAAI00768)

TGFBR1 Antibody (Phospho-S165) (OAAI00768)

555,00 €

Zzgl. MwSt.

ArtNr	OAAI00768
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neuroinflammation Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Culture Cytokines Mesothelioma Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Format	Liquid. This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH 7.2) containing antibody stabilizer.
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, ALK-5, LDS1A, LDS2A, TGFR-1, ACVRLK4
Similar products	ACVRLK4, ALK5, SKR4, ESS1, AAT5, ALK-5, LDS1A, LDS2A, TGFR-1, LDS1, MSSE
Lieferbar
Gene symbol	TGFBR1
Molecular weight	ca.55 kDa
Product format	Liquid. PBS (pH 7.2) containing antibody stabilizer.
Gene id	7046
Reconstitution and storage	The antibodies are stable for 12 months from date of receipt when stored at -20° C to -70° C. The antibodies can be stored at 2° C to 8° C for three months without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Description of target	Transforming growth factor beta isoforms (TGF-beta1, 2, 3) play vital roles in regulating cellular growth and differentiation, and they signal throμ gh a highly restricted subset of receptors known as TGF-beta type I receptor (TbetaR-I) and TGF-beta type II receptor (TbetaR-II). Expression of T beta R-I is more ubiquitous than that of T beta R-II. There was no staining of T beta R-II in the central nervous system, while intense T beta R-I staining was found specifically in nervous tissues. Expression of T beta R-I and T beta R-II was mostly coincident with that of their ligands, sμ ggesting that TGF-beta s act as multiple mediators during organogenesis. TGF-beta binds with high affinity to its receptor, a transmembrane protein with a cytoplasmic serine/threonine kinase domain, to form a dynamic dimer with phosphorylation in the cytoplasmic Ser/Thr residuals which cause its kinase activity and association with another TGF beta-binding protein, the type I receptor, to signal growth inhibition and early gene responses.
Purification	Purified by Site-specific Epitope Affinity Purification.
Clonality	Polyclonal
Immunogen	A synthetic peptide derived from internal sequence (-EEDP-*S-LDRP) with a phosphorylation site at Serine 165 of Mouse TGFbeta receptor type-1. This sequence is also identical within Human, Rat, Mouse, chicken, bovine and dog species.
Drywet	Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

Listenpreis: 555,00 €

Preis: 555,00 €

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Lieferung vsl. bis 11.09.2025

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