Sin Nombre Virus Nucleocapsid Antibody

blue ice or RT

Sin Nombre virus nucleocapsid antibody was raised against a 19 amino acid peptide near the center of the Sin Nombre virus nucleocapsid.

The immunogen is located within amino acids 170 - 220 of Sin Nombre Virus Nucleocapsid.

N/A

Polyclonal

Unconjugated

1 mg/mL

Cat. No. 7685P – Sin Nombre Virus Nucleocapsid Peptide

None

AAG03030

2943142

SNVsSgp1

Sin Nombre virus

Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). The hantavirus nucleocapsid protein plays several roles in viral replication and assembly, and is the major antigen in humoral responses in humans and mice (2). Within the bunyviridae family, the nucleocapsid protein also functions as an RNA chaperone facilitating the formation of the stable genomic RNA “panhandle” and is thought to aid in the replication of bunyavirus RNA (3).

Tischler ND, Rosemblatt M, and Valenzuela PD. Characterization of cross-reactive and serotype-specific epitopes on the nucleocapsid proteins of hantaviruses. Virus Res. 2008; 135:1-9.