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CD86 Antibody [24F] (FITC)

CD86 Antibody [24F] (FITC)

652,00 €

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ArtNr	PRS-76-608-0.5mg
Hersteller	ProSci
Menge	0.5 mg
Kategorie	Neuroscience Neural Lineage Markers Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC
Specific against	Rat (Rattus norvegicus)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	B7-2, Cd86
Lieferbar
Shipping	blue ice or RT
By Research Area	Innate Immunity
Specificity	The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality	Monoclonal
Clone	24F
Isotype	Mouse IgG1, kappa
Conjugate	FITC
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration	batch dependent
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	Cd86
Ncbi Gene Id #	56822
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	Cd86
Ncbi Official Full Name	CD86 molecule
Ncbi Organism	Rattus norvegicus
Background	The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions. The 24F antibody is capable of blocking the co-stimulatory activity of CD86.
Background References 1	Hathcock, K. S., Laszlo, G., Dickler, H. B., Bradshaw, J., Linsley, P., Hodes, R. J. (1993). Identification of an alternative CTLA-4 ligand costimulatory for T cell activation.Science, 262(5135), 905-907.
Background References 2	Inaba, K., Witmer-Pack, M., Inaba, M., Hathcock, K. S., Sakuta, H., Azuma, M., ... Steinman, R. M. (1994). The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.The Journal of experimental medicine, 180(5), 1849-1860.
Background References 3	Hathcock, K. S., Laszlo, G., Pucillo, C., Linsley, P., Hodes, R. J. (1994). Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.The Journal of experimental medicine, 180(2), 631-640.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.5 mg

Listenpreis: 652,00 €

Preis: 652,00 €

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