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CD86 Antibody [24F] (FITC)

483,00 €
Zzgl. MwSt.
ArtNr PRS-76-606-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Monoclonal
Format liquid
Applikationen FC
Specific against Rat (Rattus norvegicus)
Host Mouse
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias B7-2, Cd86
Lieferbar
Shipping
blue ice or RT
By Research Area
Innate Immunity
Specificity
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality
Monoclonal
Clone
24F
Isotype
Mouse IgG1, kappa
Conjugate
FITC
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration
batch dependent
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
Cd86
Ncbi Gene Id #
56822
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
Cd86
Ncbi Official Full Name
CD86 molecule
Ncbi Organism
Rattus norvegicus
Background
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions. The 24F antibody is capable of blocking the co-stimulatory activity of CD86.
Background References 1
Maeda, K., Sato, T., Azuma, M., Yagita, H., Okumura, K. (1997). Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology, 9(7), 993-1000.
Background References 2
Damoiseaux, J. G., Yagita, H., Okumura, K., van Breda Vriesman, P. J. (1998). Costimulatory molecules CD80 and CD86 in the rat
Background References 3
tissue distribution and expression by antigen-presenting cells.Journal of leukocyte biology, 64(6), 803-809.
Background References 4
BLUESTONE, J. (1995). New perspectives of CD28-B7-mediated T cell costimulation.Immunity, 2, 555-559.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
Listenpreis: 483,00 €
Preis: 483,00 €
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Lieferung vsl. bis 04.09.2025 

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