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CD30 Antibody [mCD30.1]

CD30 Antibody [mCD30.1]

710,00 €

Zzgl. MwSt.

ArtNr	PRS-76-018-0.5mg
Hersteller	ProSci
Menge	0.5 mg
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Mesothelioma Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ki, Cd30, Ki-1, D1S166E, Tnfrsf8
Lieferbar
Shipping	blue ice or RT
By Research Area	Apoptosis, Functional Assays
Specificity	The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily.
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality	Monoclonal
Clone	mCD30.1
Isotype	Armenian Hamster IgG
Conjugate	Unconjugated
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Concentration	batch dependent
Storage Conditions	The product should be stored undiluted at 4˚ C . Do not freeze.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	Tnfrsf8
Ncbi Gene Id #	21941
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	Tnfrsf8
Ncbi Official Full Name	tumor necrosis factor receptor superfamily, member 8
Ncbi Organism	Mus musculus
Swissprot #	Q60846
Background	The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.
Background References 1	Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., Lyons, P. A. (2000). Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2.Diabetes, 49(9), 1612-1616.
Background References 2	Falini, B., Pileri, S., Pizzolo, G., D, H., Flenghi, L., Stirpe, F., ... Stein, H. (1995). CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.BLOOD-NEW YORK-, 85, 1-1.
Background References 3	Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., Miller, J. F. (1999). CD 30 prevents T‐cell responses to non‐lymphoid tissues.Immunological reviews, 169(1), 23-29.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.5 mg

Listenpreis: 710,00 €

Preis: 710,00 €

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