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Natriuretic Peptide Receptor C Antibody

645,00 €
Zzgl. MwSt.
ArtNr PRS-63-401-200ul
Hersteller ProSci
Menge 200 ul
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Atrial natriuretic peptide receptor 3, Atrial natriuretic peptide clearance receptor, Atrial natriuretic peptide receptor type C, ANP-C, ANPR-C, NPR-C, NPR3, ANPRC, C5orf23, NPRC
Lieferbar
Shipping
blue ice or RT
By Research Area
Signal Transduction
Immunogen
This Natriuretic Peptide Receptor C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-97 amino acids from the N-terminal region of human Natriuretic Peptide Receptor C.
Applications
For WB starting dilution is: 1:1000

For IF starting dilution is: 1:200

For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight
60 kDa
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
NPR3
Accession #
P17342
Protein Gi #
27735161
Ncbi Gene Id #
4883
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
NPR3
Ncbi Official Full Name
Atrial natriuretic peptide receptor 3
Ncbi Organism
Homo sapiens
Swissprot #
P17342
Background
ANPC is a receptor for atrial natriuretic peptide. It does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.
Background References 1
References for protein:
Background References 2
Porter, J.G., et al., Biochem. Biophys. Res. Commun. 171(2):796-803 (1990).
Background References 3
Lowe, D.G., et al., Nucleic Acids Res. 18 (11), 3412 (1990).
1st Image Caption
Western Blot at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: HL-60 whole cell lysate Lysates/proteins at 20 ug per lane.
2nd Image Caption
Fluorescent confocal image of HeLa cells stained with Natriuretic Peptide Receptor C antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.2%, 30 min). Cells were then incubated with Natriuretic Peptide Receptor C primary antibody (1:200, 2 h at room temperature). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:1000, 1h). Nuclei were counterstained with Hoechst 33342 (blue) (10 ug/ml, 5 min). Note the highly specific localization of the Natriuretic Peptide Receptor C mainly to the mainly to the nucleus.
3rd Image Caption
Natriuretic Peptide Receptor C (NPR3/ANPC) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Natriuretic Peptide Receptor C (NPR3/ANPC) Antibody for immunohistochemistry.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ul
Lieferbar: In stock
Listenpreis: 645,00 €
Preis: 645,00 €
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Lieferung vsl. bis 07.08.2025 

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