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FOLR2 Antibody

645,00 €
Zzgl. MwSt.
ArtNr PRS-61-763-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, FC, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Lieferbar
Shipping
blue ice or RT
By Research Area
Immunology, Obesity, Signal Transduction
Immunogen
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human FOLR2.
Applications
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight
29 kDa
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
FOLR2
Accession #
P14207
Protein Gi #
116241366
Ncbi Gene Id #
2350
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
FOLR2
Ncbi Official Full Name
Folate receptor beta
Ncbi Organism
Homo sapiens
Swissprot #
P14207
Background
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
Background References 1
Puig-Kroger, A., et al. Cancer Res. 69(24):9395-9403(2009) Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009) Franke, B., et al. Birth Defects Res. PartClin. Mol. Teratol. 85(3):216-226(2009)
1st Image Caption
Western blot analysis of lysate from human placenta tissue, using FOLR2 Antibody at 1:1000.
2nd Image Caption
Western blot analysis of lysates from MDA-MB-453 cell line, human placenta tissue lysate (from left to right), using FOLR2 Antibody at 1:1000 at each lane.
3rd Image Caption
Western blot analysis of lysate from human placenta tissue lysate, using FOLR2 Antibody at 1:1000.
4th Image Caption
Western blot analysis of lysate from human placenta tissue lysate, using FOLR2 Antibody at 1:1000.
5th Image Caption
Western blot analysis of lysates from KG-1, MCF-7, MDA-MB-453 cell line (from left to right), using FOLR2 Antibody at 1:1000 at each lane.
6th Image Caption
Western blot analysis of lysate from mouse heart tissue lysate, using FOLR2 Antibody at 1:1000.
7th Image Caption
FOLR2 Antibody IHC analysis in formalin fixed and paraffin embedded human spleen followed by peroxidase conjugation of the secondary antibody and DAB staining.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
Listenpreis: 645,00 €
Preis: 645,00 €
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Lieferung vsl. bis 04.09.2025 

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