CD70 Antibody

645,00 €

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ArtNr	PRS-57-954-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Uterine, Ovarian & Cervical Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7
Lieferbar
Shipping	blue ice or RT
By Research Area	Cancer, Immunology, Signal Transduction
Immunogen	This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight	21 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CD70
Accession #	P32970
Protein Gi #	21431837
Ncbi Gene Id #	970
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CD70
Ncbi Official Full Name	CD70 antigen
Ncbi Organism	Homo sapiens
Swissprot #	P32970
Background	The protein encoded by this gene is a cytokine thatbelongs to the tumor necrosis factor (TNF) ligand family. Thiscytokine is a ligand for TNFRSF27/CD27. It is a surface antigen onactivated, but not on resting, T and B lymphocytes. It inducesproliferation of costimulated T cells, enhances the generation ofcytolytic T cells, and contributes to T cell activation. Thiscytokine is also reported to play a role in regulating B-cellactivation, cytotoxic function of natural killer cells, andimmunoglobulin sythesis.
Background References 1	Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010)
Background References 2	Shaw, J., et al. Blood 115(15):3051-3057(2010)
Background References 3	Yu, S.E., et al. Mol. Cells 29(2):217-221(2010)
Background References 4	Kozlowska, A., et al. J. Rheumatol. 37(1):53-59(2010)
1st Image Caption	Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
2nd Image Caption	CD70 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Preis: 645,00 €

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