CXCR2 Antibody

451,00 €

Zzgl. MwSt.

ArtNr	PRS-19-026-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cxcr2, mIL-8RH, interleukin-8 receptor type B, interleukin 8 receptor, beta, IL-8Rh, IL-8rb, Il8rb, IL8RA, IL-8R B, IL-8 receptor alpha chain, high affinity interleukin-8 receptor B, GRO/MGSA receptor, Gpcr16, CXC-R2, CXCR-2, C-X-C chemokine receptor type
Lieferbar
Shipping	blue ice or RT
By Research Area	Apoptosis, Cell Cycle, Immunology, Signal Transduction
Immunogen	Recombinant protein of human CXCR2.
Applications	WB: 1:500 - 1:2000
Positive Control 1	A-549
Positive Control 2	HepG2
Positive Control 3	mouse spleen
Positive Control 4	mouse lung
Positive Control 5	rat spleen
Positive Control 6	rat lung
Predicted Molecular Weight	Observed: 41kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CXCR2
Ncbi Gene Id #	3579
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CXCR2
Ncbi Official Full Name	chemokine (C-X-C motif) receptor 2
Ncbi Organism	Homo sapiens
Swissprot #	P25025
Background	The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
1st Image Caption	Western blot analysis of extracts of various cell lines, using CXCR2 antibody (19-026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 50 uL

Listenpreis: 451,00 €

Preis: 451,00 €

lieferbar

Lieferung vsl. bis 04.09.2025

Anzahl:

Vergleichen