CHRM2 Antibody

451,00 €

Zzgl. MwSt.

ArtNr	PRS-16-170-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Neuroscience Neural Signaling Assisted reproductive technologies Embryo manipulation Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	7TM receptor, cholinergic receptor, muscarinic 2, CHRM2, FLJ43243, HM2, MGC120006, MGC120007, muscarinic acetylcholine receptor M2, muscarinic M2 receptor, OTTHUMP00000208393, OTTHUMP00000208394, OTTHUMP00000208395, OTTHUMP00000208396
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Shipping	blue ice or RT
By Research Area	Neuroscience, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human CHRM2 (NP_001006629.1).
Applications	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Positive Control 1	SH-SY5Y
Positive Control 2	HepG2
Predicted Molecular Weight	Observed: 52kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CHRM2
Ncbi Gene Id #	1129
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CHRM2
Ncbi Official Full Name	cholinergic receptor, muscarinic 2
Ncbi Organism	Homo sapiens
Swissprot #	P08172
Background	The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
1st Image Caption	Western blot analysis of extracts of various cell lines, using CHRM2 antibody (16-170) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
2nd Image Caption	Immunofluorescence analysis of MCF-7 cells using CHRM2 antibody (16-170). Blue: DAPI for nuclear staining.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Preis: 451,00 €

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