ESRRA Antibody

451,00 €

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ArtNr	PRS-15-414-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1, ESRRA, ERR1, ESRL1, NR3B1
Lieferbar
Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction, Transcription
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-423 of human ESRRA (NP_004442.3).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Positive Control 1	293T
Positive Control 2	Mouse kidney
Positive Control 3	Mouse heart
Positive Control 4	Rat heart
Predicted Molecular Weight	Observed: 46kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ESRRA
Ncbi Gene Id #	2101
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ESRRA
Ncbi Official Full Name	Steroid hormone receptor ERR1
Ncbi Organism	Homo sapiens
Swissprot #	P11474
Background	The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene.
1st Image Caption	Western blot analysis of extracts of various cell lines, using ESRRA antibody (15-414) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded human uterus using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded rat testis using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
4th Image Caption	Immunohistochemistry of paraffin-embedded rat liver using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
5th Image Caption	Immunohistochemistry of paraffin-embedded rat brain using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
6th Image Caption	Immunohistochemistry of paraffin-embedded mouse heart using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
7th Image Caption	Immunohistochemistry of paraffin-embedded mouse lung using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
8th Image Caption	Immunohistochemistry of paraffin-embedded mouse kidney using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
9th Image Caption	Immunohistochemistry of paraffin-embedded mouse brain using ESRRA antibody (15-414) at dilution of 1:200 (40x lens).
10th Image Caption	Immunohistochemistry of paraffin-embedded human uterus using TFAM antibody (15-064) at dilution of 1:100 (40x lens).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Preis: 451,00 €

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