RBBP7 Antibody

451,00 €

Zzgl. MwSt.

ArtNr	PRS-14-998-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies CHiP By Organ Head & Neck Cancer
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC, CHIP
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
Lieferbar
Shipping	blue ice or RT
By Research Area	Cell Cycle
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RBBP7 (NP_002884.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200 ChIP: 1:50 - 1:200
Positive Control 1	HT-29
Positive Control 2	MCF7
Positive Control 3	293T
Predicted Molecular Weight	Observed: 48kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	RBBP7
Ncbi Gene Id #	5931
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	RBBP7
Ncbi Official Full Name	Histone-binding protein RBBP7
Ncbi Organism	Homo sapiens
Swissprot #	Q16576
Background	This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
1st Image Caption	Western blot analysis of extracts of various cell lines, using RBBP7 antibody (14-998) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded human gastric cancer using RBBP7 antibody (14-998) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunofluorescence analysis of MCF7 cells using RBBP7 antibody (14-998). Blue: DAPI for nuclear staining.
4th Image Caption	Chromatin immunoprecipitation analysis of extracts of 293T cells, using RBBP7 antibody (14-998) and rabbit IgG. The amount of immunoprecipitated DNA was checked by quantitative PCR. Histogram was constructed by the ratios of the immunoprecipitated DNA to the input.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

Listenpreis: 451,00 €

Preis: 451,00 €

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